How Different Sexes Are Impacted By Sleep Loss

New research indicates that pulling an all-nighter can impact women’s memory significantly more strongly than men.

Over the last few decades, science has learned that lack of sleep harms your mind and body in a number of ways, particularly your memory. Working memory is important for keeping things in mind for briefer periods of time, which thereby facilitates reasoning and planning. A team of sleep scientists from Uppsala University now demonstrates that acute sleep loss impacts working memory differently in women and men.

In the study, 24 young adults performed a working memory task in the morning following either a full night of sleep or a night of wakefulness. Half of the participants were females, and half were males. The set-up of the working memory task was to learn and remember 8-digit sequences. Contrary to expectations, males’ working memory performance remained unaffected by sleep loss. In contrast, females remembered fewer digits after sleep loss than after a night of sleep.

In addition to the findings about the differences in impact to men and women, the study also found that women seemed to be unaware of their drop in memory performance.  A lack of awareness of impaired mental performance could increase the risk of accidents and mistakes, which can be dangerous in many private and occupational situations, both for the sleep-deprived person as well as for others.

“Our study suggests that particular attention should be paid to young women facing challenges in which they have to cope with both a high working memory load and a lack of sleep. However, it must be kept in mind that we have not tested whether the observed sex-dependent effects of sleep loss on working memory during morning hours would also occur at other time points of the day.,” says Frida Rångtell, PhD student at the Department of Neuroscience and lead author of the study.

“In addition, while our data suggest that sleep loss impairs working memory in a sex-dependent manner, this does not mean that the sex-differences we observed can be generalized to other mental or physical measures of how we are affected by sleep loss.

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